Product ID:CYCLOPHOSPHAMIDE USP
MSDS Date:11/08/1985
FSC:6505
NIIN:00-733-5246
MSDS Number: BFMSN

Emergency Phone: 614 221-5574

Cage: OOO22

Telephone: 614 221-5574

Cage: OOO22

CYCLOPHOSPHAMIDE (SARA III)

CAS: 50-18-0

RTECS: RP5950000

Fraction By Weight: 69%

EPA Report Quantity: 10 LBS

DOT Report Quantity: 10 LBS

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:YES
Health Hazards Acute and Chronic:ACUTE:NAUSEA,VOMITING,LEUKOPENIA,HAIR
LOSS. CHRONIC:LEUKOPENIA,HAIR LOSS,CYSTITIS.
Explanation of Carcinogenicity:NTP-LISTED AS KNOWN TO BE
CARCINOGENIC.IARC-SUPPLEMENT 4 LISTED"SUFFICIENT EVIDENCE FOR
CARCINICITY IN HUMANS (SUPP DATA
Effects of Overexposure:NAUSEA,VOMITING,LEUKOPENIA HAIR LOSS.
Medical Cond Aggravated by Exposure:UNDETERMINED

First Aid:INHALE:SEEK MEDICAL ATTENTION EYE:IRRIGATE WITH COPIOUS
AMOUNTS OF WATER OR PHYSIOLOGICAL SALINE FOR AT LEAST 15
MINUTES.SKIN:WASH WITH SOAP AND WATER.INGESTION:SEEK MEDICAL
ATTENTION.

Flash Point:NA
Lower Limits:NONFLAMMABLE
Upper Limits:NONFLAMMABLE
Extinguishing Media:NA
Fire Fighting Procedures:NA
Unusual Fire/Explosion Hazard:WHEN HEATED TO DECOMPOSITION IT EMIT
HIGHLY TOXIC FUMES OF OXIDES OF PHOSPHOROUS AND NITROGEN.

Spill Release Procedures:WASH AREA WITH COPIOUS AMOUNTS OF WATER.

Handling and Storage Precautions:POTENT ANTI-CANCER DRUG.CAUTION IN THE
HANDLING AND USE MUST BE EXERCISED.IF POWDER OR SOLUTION CONTACTS
SKIN OR MUCOSAE.WASH THOROUGHLY W/SOAP & H*2O
Other Precautions:SEE PRODUCT INSERT FOR FURTHER INFORMATION

Respiratory Protection:APPROVED TOXIC DUST MASK OR AEROSOL MASK(MFG)USE
NIOSH/MSHA APPROVED RESPIRATOR APPROPRIATE FOR EXPOSURE OF CONCERN
Ventilation:LOCAL:VERTICAL LAMINAR FLOW HOOD. HEPA FILTER TO OUTSIDE
Protective Gloves:SYNTHETIC OR RUBBER GLOVES
Eye Protection:SPLASH GOGGLES
Other Protective Equipment:LONG SLEEVE,IMPERMEABLE DISPOSABLE GOWN WITH
ELASTIC CUFFS.
Work Hygienic Practices:OBSERVE GOOD HYGIENIC WORK PRACTICES
Supplemental Safety and Health
CARC:OSHA-SUSPECT CHEMICAL SOURCEBOOK FLOOR LIST

HCC:N1
Boiling Pt:B.P. Text:NA
Melt/Freeze Pt:M.P/F.P Text:NA
Vapor Pres:NA
Vapor Density:NA
Spec Gravity:NA
Evaporation Rate & Reference:NA
Solubility in Water:40G/L
Appearance and Odor:WHITE POWDER

Stability Indicator/Materials to Avoid:YES
BENZYL ALCOHOL PRESERVED DILUENTS.
Stability Condition to Avoid:NONE
Hazardous Decomposition Products:OXIDES OF PHOSPHOROUS AND NITROGEN.
Conditions to Avoid Polymerization:WILL NOT OCCUR (MFG)

Waste Disposal Methods:MIX WITH SODIUM HYPOCHLORITE,DISPOSE IN
ACCORDANCE WITH YOUR PROCEDURE FOR HAZARDOUS WASTE DISPOSAL TO MEET
LOCAL,STATE AND FEDERAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.